Journal of American medical association, ces 60 derniers jours

Site du Journal of American medical association (JAMA)

mardi 12 février 2019

  • Contaminated Bypass Equipment
    Blood heating and cooling machines used during heart bypass were linked to 20 cases of Mycobacterium chimaera in California patients in 2016, according to a CDC report.

  • Wound Botulism Outbreak
    A rare 9-person outbreak of wound botulism in California was traced to use of black tar heroin, according to a CDC report.

  • USPSTF Recommendation: Interventions to Prevent Perinatal Depression
    This 2019 Recommendation Statement from the US Preventive Services Task Force recommends that clinicians provide or refer pregnant and postpartum persons at increased risk of perinatal depression to counseling interventions, such as cognitive behavioral or interpersonal therapy (B (...)

  • USPSTF Evidence Report: Interventions to Prevent Perinatal Depression
    This systematic review to support the 2019 US Preventive Services Task Force Recommendation Statement on interventions to prevent perinatal depression summarizes published evidence on the benefits and harms of primary care–relevant interventions to prevent depression during pregnancy or up to 1 (...)

  • JAMA
  • Permanent Ink: The Stories of Patients’ Tattoos
    In this narrative medicine essay a physician recalls the connections she has forged with patients through conversations about their tattoos and reveals how she considers herself tattooed with the narratives and experiences they’ve (...)

  • Verdict: Stage Four
    So blank, so lulled,I lived the seasons like a forest;so lank, so mild,the days disguised a warfare harvest.

  • Counseling Interventions to Prevent Perinatal Depression
    This JAMA Patient Page explains the US Preventive Services Task Force’s 2019 recommendations to provide or refer pregnant and postpartum women at risk of perinatal depression to counseling interventions such as cognitive behavioral therapy and interpersonal (...)

  • Association of LVEF and Heart Failure Symptoms With Mortality After Elective Noncardiac Surgery
    This cohort study found that 90-day mortality following elective noncardiac surgery was higher among Veterans Affairs patients with symptomatic or asymptomatic heart failure and reduced left ventricular ejection fraction (LVEF) compared with patients without heart (...)

  • Paracetamol and Ibuprofen and Morphine Consumption After Total Hip Arthroplasty
    This randomized clinical trial compares the effects of combination paracetamol (acetaminophen) and ibuprofen at full vs half strength vs either drug alone on 24-hour patient-controlled morphine consumption and 90-day serious adverse events after total hip arthroplasty (...)

  • Antibiotics for Ceftriaxone Resistant Gram-Negative Bacterial Bloodstream Infections—Reply
    In Reply Dr Rodríguez-Baño and colleagues comment that our findings, in which 30-day all-cause mortality was 12.3% (23/187) of patients randomized to piperacillin-tazobactam compared with 3.7% (7/191) randomized to meropenem, stand in contrast to retrospective observational studies in which (...)

  • Age of Initiation of Cervical Cancer Screening—Reply
    In Reply Dr Dickinson raises the question as to why the USPSTF recommended screening for cervical cancer with cervical cytology every 3 years in women aged 21 to 29 years (A recommendation) rather than starting at age 25 years. In support of starting screening at a later age, he cites the low (...)

  • Antibiotics for Ceftriaxone-Resistant Gram-Negative Bacterial Bloodstream Infections
    To the Editor Dr Harris and colleagues conducted a well-designed study investigating whether carbapenems for extended-spectrum β-lactamase–producing enterobacteria could be spared. The results should be interpreted with caution.

  • Antibiotics for Ceftriaxone-Resistant Gram-Negative Bacterial Bloodstream Infections
    To the Editor The MERINO trial found that piperacillin-tazobactam did not result in noninferior 30-day mortality in patients with Escherichia coli or Klebsiella pneumoniae bloodstream infections and ceftriaxone resistance, compared with meropenem. We think there might be reasons to explain the (...)

  • Age of Initiation of Cervical Cancer Screening
    To the Editor The US Preventive Services Task Force (USPSTF) recently recommended screening for cervical cancer every 3 years with cervical cytology in women aged 21 to 29 years (A recommendation). I question why cervical screening is recommended starting at age 21 years rather than 25 years. (...)

  • Accuracy of CMS’ Opioid Overutilization Criteria for Classifying Opioid Use Disorder or Overdose
    This study characterizes the accuracy of CMS’ Overutilization Monitoring System for correctly identifying prescription opioid users at risk of opioid use disorder (OUD) or overdose between 2011 and 2014.

  • Buprenorphine Coverage in the Medicare Part D Program for 2007 to 2018
    This study uses Medicare Part D prescription drug plan formulary files to characterize changes in coverage of buprenorphine and buprenorphine-naloxone for opioid use disorder in 2007, 2012, and 2018.

  • Literature as an Aid to Restoration
    The war, which has in greater or lesser degree affected all the civilized nations of the earth, has given rise to novelties of performance and innovations of thought entirely unanticipated. Aside from the institution of new devices and operations that have demanded unusual ingenuity on the part (...)

  • The 2018 Midterm Election Results and Health Care
    With the midterm elections receding, the country’s attention is already focused on 2020 and the most likely candidate to secure the Democratic presidential nomination. No matter which candidate it is, health care and the future direction of health care in the United States is likely to have a (...)

  • Highlights for February 12, 2019
  • Prevention of Perinatal Depression
    In this issue of JAMA, the US Preventive Services Task Force (USPSTF) recommends “that clinicians provide or refer pregnant and postpartum persons who are at increased risk of perinatal depression to counseling interventions” (B recommendation; net benefit is moderate). This recommendation is (...)

  • New Deep Brain Stimulation Target for Mood Disorders
    Deep brain stimulation of the lateral orbitofrontal cortex (OFC) improved depression symptoms in a study involving 25 patients with epilepsy at the University of California, San Francisco. The discovery adds a new electrical stimulation target to the handful of brain regions currently under (...)

  • Advanced Brain-Computer Interface for People With Paralysis
    In a recent study in PLOS One, a 63-year-old man with tetraplegia caused by a spinal cord injury sent his first text messages with an off-the-shelf consumer tablet paired to an intracortical brain-computer interface (iBCI). He and 2 other participants with limited arm and hand mobility due to (...)

  • Imaging Needle to Detect Blood Vessels During Brain Tumor Biopsy
    Before a patient with a brain tumor undergoes a needle biopsy, magnetic resonance imaging (MRI) is used to locate the mass and major blood vessels. During the biopsy, the position of the needle is tracked with sensors and superimposed onto the scan, allowing the surgeon to sample the tumor (...)

  • The Rise of Pseudomedicine for Dementia and Brain Health
    This Viewpoint discusses the growing market for complementary interventions to prevent cognitive impairment and promote brain health, and urges health care professionals to partner with patients to address their health concerns and help them understand the market forces behind unproven (...)

  • Effect of Intensive vs Standard Blood Pressure Control on Probable Dementia
    This randomized clinical trial compares the effect of treating adults with hypertension to a systolic blood pressure (SBP) goal of less than 120 mm Hg vs treating to a goal of less than 140 mm Hg on risk of probable dementia and mild cognitive (...)

  • Prevention of Cognitive Impairment With Intensive Systolic Blood Pressure Control
    The prevalence of Alzheimer disease (AD) and related dementia is expected to triple over the next 30 years in the United States and worldwide. Alzheimer disease drug development during the past 2 decades has met with disappointment. The last drug approved for this disease by the US Food and (...)

  • A Framework for Increasing Trust Between Patients and the Organizations That Care for Them
    This Viewpoint summarizes key findings and conclusions of a working group of health care leaders and patient advocates who participated in a 2018 American Board of Internal Medicine (ABIM) Foundation Forum on [Re]Building Trust, convened to identify and prioritize interventions to restore trust (...)

  • Using the E-Value to Assess the Potential Effect of Unmeasured Confounding in Observational Studies
    This Guide to Statistics and Methods discusses E-value analysis, an alternative approach to sensitivity analyses for unmeasured confounding in observational studies that specifies the degree of unmeasured confounding that would need to be operative to negate observed results in a (...)

  • Trust in Health Care
    Trust is defined by the Merriam-Webster dictionary as “assured reliance on the character, ability, strength, or truth of someone or something.” The Oxford dictionary has a similar definition: “firm belief in the reliability, truth, or ability of someone or (...)

  • New Planned Parenthood President: No Politics in the Exam Room
    This Medical News article is an interview with Leana Wen, MD, the new president of Planned Parenthood.

  • Increasing the Rate of Smoking Cessation in the United States
    This Viewpoint argues that adoption of a combination of varenicline, nicotine replacement therapy, and behavioral support as first-line treatment for tobacco addiction could increase smoking cessation rates in the United States and proposes that varenicline be made an over-the-counter (...)

  • A Fussy Infant With a Generalized Papulovesicular Rash
    A previously healthy 7-week-old infant had a 4-week history of a worsening, widespread, papulovesicular rash with nighttime irritability and restlessness; burrows were present, and Gram stain, potassium hydroxide preparation, and Tzanck smear were negative. A babysitter reported having (...)

  • The Waverly Gallery —Dementia on Broadway
    This Arts & Medicine essay reviews the 2018-2019 Broadway revival of The Waverly Gallery, a Kenneth Lonergan play that tells the story of the effects within a well-to-do Manhattan family of the decline of a family member from progressive (...)

mardi 5 février 2019

  • JAMA
  • Will This Patient Be Difficult to Intubate?
    This Rational Clinical Examination systematic review characterizes the accuracy of clinical features and bedside tests for predicting difficult endotracheal intubation.

  • Losing Vision and Gaining Perspective
    In this narrative medicine essay, a researcher diagnosed with degenerative retinal disease discusses the challenge of being a scientist with a disability and describes how she worked through institutional barriers, depression, and fear with help from peers and mentors to bring insights and (...)

  • The Body Is the Person
    The body is the personwho we cannot leave—made bit by bitwe hope with tenderness,vulnerable in the womband after the first breath,since an egg accepted a spermwhether in a coral showeror a dance of whales,whether on a mountain or in tidal poolsor in the warm shell of the placentawhere compassion (...)

  • Genital Warts
    This JAMA Patient Page describes genital warts and their cause, risk factors, treatment, and prevention.

  • EEG Guidance of Anesthesia and Postoperative Delirium
    This pragmatic randomized trial compares the effects of EEG-guided anesthetic administration vs usual anesthetic care on incident postoperative delirium among older adults undergoing major surgery.

  • Association of Type 1 Diabetes With Standardized Test Scores of Danish Schoolchildren
    This population-based cohort study compares standardized reading and mathematics test scores of Danish public schoolchildren with vs without type 1 diabetes to assess the association between diabetes and school performance.

  • Effect of MRI vs Conventional Treat-to-Target Strategies on Disease Activity Remission in RA
    This randomized clinical trial compares the effect of a magnetic resonance imaging (MRI)–guided vs a conventional clinical treat-to-remission-target strategy on improving disease activity scores and radiographic progression in patients with rheumatoid arthritis (RA) in clinical (...)

  • Imvexxy – Another Estradiol Vaginal Insert for Dyspareunia
    This Medical Letter review summarizes doses and formulations of Imvexxy, an estradiol softgel vaginal insert that was recently approved to treat moderate to severe dyspareunia due to vulvovaginal atrophy in postmenopausal women.

  • Physician Burnout—Reply
    In Reply As we said in our Editorial, we agree completely with Dr Levine that something important and serious is affecting the work satisfaction of physicians. Whatever it is requires attention and solution. However, burnout is so heterogeneous in its makeup and assessment that any solutions (...)

  • Treatment of Recurrent Clostridium difficile Infection—Reply
    In Reply We believe that the recent IDSA/SHEA guidelines on diagnosis and treatment of CDI are a significant update and provide treating clinicians with tools to better diagnose and manage CDI. There have been some important changes from earlier guidelines. We agree that the recommendations for (...)

  • Palliative Care for Patients With Opioid Misuse—Reply
    In Reply In response to our Viewpoint highlighting educational, research, and policy issues raised by use of palliative care earlier in the disease course in the context of the opioid epidemic, Dr Hui and colleagues note that palliative care specialists have long recognized opioid use disorders (...)

  • Physician Burnout
    To the Editor In their Editorial on physician burnout, Drs Schwenk and Gold missed an opportunity to enhance efforts to address the burnout problem. They called for increased research into burnout to better define its scope and (...)

  • Treatment of Recurrent Clostridium difficile Infection
    To the Editor Dr Gupta and colleagues summarized 4 of the major new recommendations in the updated guidelines from the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA) on the diagnosis and treatment of Clostridium difficile infection (CDI). (...)

  • Palliative Care for Patients With Opioid Misuse
    To the Editor We agree with Dr Schenker and colleagues that palliative care teams are well positioned to support patients with advanced illnesses and concurrent nonmedical opioid use because of their clinical expertise in symptom management, interdisciplinary nature, and emphasis on (...)

  • Association Between Value-Based Incentive Programs and ICU Catheter-Associated Urinary Tract Infections
    This before-after study examines the association between value-based incentive programs that link financial rewards and penalties to hospital performance on quality indicators and catheter-associated urinary tract infection outcomes in intensive care units (...)









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